Publications

2022

• Faez S. Alotaibi, Michael R. Chhoun, and Gregory R. CookPd-NHC Catalysis in Cross Coupling of Amides. In Amide Bond Activation Szostak, M. Ed.; Wiley-VCH, Weinheim. 2022, pp 273-288. (book chapter)

• Vemula S, Kumar D, Cook G. pi-Bond Directed C-2 Amination of Indoles: Catalysis Development, Mechanistic Investigation, and Substrate Scope . ChemRxiv. Cambridge: Cambridge Open Engage; 2022; This content is a preprint and has not been peer-reviewed.
  https://chemrxiv.org/engage/chemrxiv/article-details/634830c9a2c7907533460449

   

2019

• Well Defined Precatalysts in Amide and Ester Bond Activation Sandeep R Vemula, Michael R. Chhoun, and Gregory R. Cook* Molecules, 2019, 24(2), 215. invitedreview
  DOI: 10.3390/molecules24020215
  

2018

• Bismuth-catalyzed synthesis of 2-substituted quinazolinones Sandeep R Vemula, Dinesh Kumar, and Gregory R. Cook* Tetrahedron Lett., 2018, 59,  3801-3805.
  DOI: 10.1016/j.tetlet.2018.09.014

2016

• Indium-Mediated Stereoselective Allylation Dinesh Kumar, Sandeep R. Vemula, Balasubramanian Narayanaganesh, and Gregory R. Cook* Acc. Chem. Res., 2016, 49,  2169–2178
  DOI: 10.1021/acs.accounts.6b00362
• Palladium-Catalyzed Allylic Amidation with N-Heterocycles via sp³ C-H Oxidation Sandeep R. Vemula, Dinesh Kumar, and Gregory R. Cook ACS Catalysis, 2016, 6, 5295–5301.
  DOI: 10.1021/acscatal.6b01818
• Recent advances in the catalytic synthesis of α-ketoamides Dinesh Kumar, Sandeep R. Vemula, Gregory R. Cook* ACS Catalysis 2016, 6, 4920–4945.
  DOI: 10.1021/acscatal.6b01116
• Merging C–H Bond Functionalization with Amide Alcoholysis: En Route to 2-Aminopyridine Dinesh Kumar, Sandeep R. Vemula, and Gregory R. Cook* ACS Catalysis 2016, 6, 3531–3536
  DOI: 10.1021/acscatal.6b00728

2015

• Highly chemo- and regioselective allylic substitution with tautomerizable heteroarenes Dinesh Kumar, Sandeep R. Vemula, Gregory R. Cook* Green Chemistry2015, 17, 4300-4306
  DOI: 10.1039/C5GC01028D
• Mechanism of N-acylthiourea Mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular levels Raushan K. Singh, Kyongshin Cho, Satish K. R. Padi, Junru Yu1, Manas Haldar, Tanmay Mandal, Changhui Yan, Gregory Cook, Bin Guo, Sanku Mallik, & D.K. Srivastava* J. Biol. Chem. 2015, 290, 6607-6619
  DOI:10.1074/jbc.M114.600627
  
• N-Boc-glycine-assisted indium-mediated allylation reaction: A sustainable approach Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook* Tetrahedron Lett. 2015, 56, 3322–3325
  special edition in honor of Prof. Harry Wasserman
  DOI:10.1016/j.tetlet.2015.01.036
  
• Highly Diastereoselective Palladium-Catalyzed Indium-Mediated Allylation of Chiral Hydrazones Narayanaganesh Balasubramanian, Tanmay Mandal, and Gregory R. Cook,* Organic Letters 2015, 17, 314–317
  DOI: 10.1021/ol503420
  

2014

• Binding Thermodynamics of Structurally Similar Ligands to Histone Deacetylase 8 Sheds Light on Challenges in Rational Design of Potent and Isozyme-selective Inhibitors of the Enzyme Raushan K Singh,* Takayoshi Suzuki, Tanmay Mandal, Narayanaganesh Balsubramanian , Manas K Haldar, Dustin J. Mueller, Jerrod A. Strode, Gregory Cook, Sanku Mallik, and D. K. Srivastava* Biochemistry 2014, 53, 7445-7458
  DOI: 10.1021/bi500711x
• Bi(OTf)₃ as a Dual Role Catalyst. Synthesis of Substituted Morpholine Derivatives via Catalytic O-Alkylation Ryuji Hayashi, Jin-A Park, and Gregory R. Cook* Heterocycles 2014, 88, 1477-1489.
  special edition in honor of Prof. Victor Snieckus
  DOI: 10.3987/COM-13-S(S)116
  

2013

• Kinetic and Thermodynamic Rationale for SAHA Being a Preferential Human HDAC8 Inhibitor as Compared to the Structurally Similar Ligand, TSA Raushan K Singh*, Naveena Lall, Travis S. Leedahl, Abigail McGillivray, Tanmay Mandal, Manas K Haldar, Sanku Mallik, Gregory Cook, and D. K. Srivastava* Biochemistry 2013, 52, 8139-8149.
  DOI: 10.1021/bi400740x

2011

• Histone Deacetylase Activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate Singh, Raushan K.; Mandal, Tanmay; Balasubranian, Narayanaganesh, Viaene, Tajae; Leedahl, Travis; Sule, Nitesh; Cook, Gregory; Srivastava, D. K. Biorg. Med. Chem. Lett. 2011, 21, 5920-5923.
  doi:10.1016/j.bmcl.2011.07.080
  PMID 21865040 : PMCID: PMC3171571
• Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors Singh, Raushan, K.; Mandal, Tanmay; Balasubramanian, Narayanaganesh; Cook, Gregory; Srivastava, D. K. Anal. Biochem. 2011, 408, 309-315.
  doi:10.1016/j.ab.2010.08.040

2009

• Chapter 21. Ring Closing Friedel-Crafts Reactions Hayashi, Ryuji; Cook, Gregory R. “Handbook of Cyclization Reactions” Ma, S., Ed.; 2009, Wiley-VCH. ISBN: 978-3-527-32088-2
• Asymmetric Synthesis of Aminochromanes via Intramolecular Indium-Mediated Allylation of Chiral Hydrazones Samanta, Debasis; Kargbo, Robert B.; Cook, Gregory R. J. Org. Chem. 2009, 74, 7183-7186.
  doi:10.1021/jo901195g

2008

• Binding of Matrix Metalloproteinase Inhibitors to Extracellular Matrix: 3D-QSAR Analysis Zhang, Y.; Lukacova, V.; Bartus, V.; Nie, X.; Sun, G.; Manivannan, E.; Ghorpade, S. R.; Jin, X.; Manyem, S.; Sibi, M. P.; Cook, G. R.; Balaz, S. Chem. Biol. Drug Des. 2008, 72, 237-248.
  doi:10.1111/j.1747-0285.2008.00710.x
• Bi(OTf)₃-Catalyzed 5-exo-trig Cyclization via Halide Activation Hayashi, Ryuji, Cook, Gregory R. Tetrahedron Lett. 2008, 49, 3888-3890.
  doi:10.1016/j.tetlet.2008.04.067

2007

• Synthesis and Evaluation of Novel Heterocyclic MMP Inhibitors Hayashi, Ryuji; Jin, Xiaomin, Cook, Gregory R. Bioorg. Med. Chem. Lett. 2007, 17, 6864-6870.
• Intermolecular Friedel-Crafts Reaction Catalyzed by InCl₃ Kaneko, Miho; Hayashi, Ryuji; Cook, Gregory R. Tetrahedron Lett. 2007, 48, 7085-7087.
• Readily Accessible, Modular and Tuneable BINOL 3,3′-Perfluoroalkylsulfones: Highly Efficient Catalysts for Enantioselective In-Mediated Imine Allylation Kargbo, Robert; Takahashi, Yoko; Bhor, Santosh; Cook, Gregory R.; Lloyd-Jones, Guy C.; Shepperson, Ian R. J. Am. Chem. Soc. 2007, 129, 3846-3847.
• Remarkably Mild and Efficient Intramolecular Friedel-Crafts Cyclization Catalyzed by In(III) Hayashi, Ryuji; Cook, Gregory R. Org. Lett. 2007, 9, 1311-1314.
• Drug-membrane Interactions Studied in Phospholipid Monolayers Adsorbed on Non-porous Alkylated Microspheres Lukacova, V.; Peng, M.; Fanucci, G.; Tandlich, R.; Hinderliter, A.; Maity, B. Manivannan, E.; Cook, Gregory R.; Balaz, S. J. Biomolecular Screening 2007, 12, 186-202.
• Stereoselective Indium-Mediated Organic Reactions Kargbo, R. B. and Cook, G. R. Current Organic Chemistry, 2007, 11, 1287.

2006

• Atom Transfer Cyclization Catalyzed by InCl₃ via Halogen Activation Cook, Gregory R. and Hayashi, Ryuji Org. Lett. 2006, 8, 1045-1048.
• Tandem Palladium-Catalyzed Allene Arylation and Oxazoline Formation Cook, Gregory R. and Xu, Wei Heterocycles 2006, 67, 215-232.
• 2,2,6-Trimethyl-4H-1,3-dioxin-4-one Cook, G. R.; Hayashi, R. Encyclopedia of Reagents for Organic Synthesis 2006, John Wiley & Sons, Ltd.
• Copper (II) Acetylacetonate Cook, G. R.; Hayashi, R. Encyclopedia of Reagents for Organic Synthesis 2006, John Wiley & Sons, Ltd.

2005

• Hydrogen Bond Directed Palladium-Catalyzed Allylic Substitution of Cyclic Substrates Cook, Gregory R.; Saraswathiamma, Manjusha Tetrahedron Lett. 2005, 38, 6491-6494.
• Chapter 21.1.4: Three Carbon-Heteroatom Bond: Amides and Derivatives; Peptides; Lactams  “Synthesis from Amines” Cook, Gregory R. Science of Synthesis, Vol 21, S. Weinreb, Ed.; 2005, Goerg Thieme Verlag KG, Stuttgart.
• Catalytic Enantioseletive Indium-Mediated Allylation of Hydrazine’s Cook, Gregory R.; Kargbo, Robert; Maity, Bikash Org. Lett. 2005, 7, 2767-2770.

2004

• Synthesis and Evaluation of Novel Oxazoline MMP Inhibitors Cook, G. R.; Manivannan, E.; Underdahl, T.; Lukacova, V.; Zhang, Y.; Balaz, S. Biorg. Med. Chem. Lett. 2004, 14, 4935-4939.
• Nitrogen Heterocycles via Palladium-Catalyzed Carbocyclization. Formal Synthesis of (+)-a-Allokainic Acid Cook, G. R.; Sun, Liangdong Org. Lett. 2004, 6, 2481-2484.
• Highly Diastereoselective Indium-Mediated Allylation of Chiral Hydrazines Cook. G. R.; Maity, B.; Kargbo, R. Org. Lett. 2004, 6, 1741-1743.

2003

• Hydrogen Bond Directed Highly Regioselective Palladium-Catalyzed Allylic Substitution Cook, Gregory R.; Yu, Hui; Sankaranarayanan, S.; Shanker, P. Sathya J. Am. Chem. Soc. 2003, 125, 5115-5120.

2002

• Stereoselective Synthesis of D-erythro-and L-threo-Sphinganines via Palladium-Catalyzed Equilibration and Suzuki Coupling Cook, G. R. and Pararajasingham, K. Tetrahedron Letters 2002, 43, 9027-9029.

2001

• Palladium-Mediated Regiodivergent Kinetic Resolution Cook, G. R.; Sankaranarayanan, S. Org. Lett. 2001, 3, 3531-3533.
• Stereoselective Synthesis of MeBmt and (4R,5S)-2-Phenyl-4-(methoxycarbonyl)-5-isopropyloxazoline by a Pd-Catalyzed Equilibration Cook, G. R.; Shankar, P. S. J. Org. Chem. 2001, 66, 6818-6822.

2000

• Transition Medal-Mediated Kinetic Resolution Cook, Gregory R. Current Organic Chemistry 2000, 4, 883.
• Copper Lewis Acids in Organic Synthesis Sibi, Mukund P.; Cook, Gregory R. Handbook of Lewis Acids; Yamamoto, H., Ed., Wiley-VCH, 2000.
• Enantioselective Reduction of Ketones using Oxazaborolidines Sibi, Mukund P.; Liu, Pingrong; Cook, Gregory R. Catalysts for the Fine Chemical Industry Roberts, S. M., Ed., Wiley, Oxford, 2000.

1999

• Asymmetric Synthesis of the Balanol Heterocycle via a Palladium-Mediated Epimerization and Olefin Metathesis Cook, Gregory R.; Shanker, P. Sathya; Peterson, Scott L. Org. Lett. 1999, 1, 615-618.
• Reversal of Stereochemistry in Diethylzinc Addition to Aldehydes by a Simple Change of the Backbone Substituent in L-Serine Derived Ligands Sibi, Mukund P.; Chen, Jian-xi; Cook, Gregory R. Tetrahedron Lett. 1999, 40, 3301-3304.
• Enantioselective Reduction of Ketones. Examination of Bifunctional Ligands Sibi, Mukund P.; Cook, Gregory R.; Liu, Pingrong Tetrahedron Lett. 1999, 40, 2477-2480.
• Palladium Mediated Dynamic Kinetic Resolution. Stereoselective Synthesis of Vicinal Diamines Cook, Gregory R.; Shanker, P. Sathya; Pararajasingham, Ketheeswaran Angew. Chem. Int. Ed. 1999, 38, 110-113.

1998

• Chloride Effect on the Palladium-Catalyzed Allylic Substitution vs Elimination of Cyclic Vinyloxazolidinones and Oxazolines Cook, Gregory R.; Shanker, P. Sathya Tetrahedron Lett. 1998, 39, 4991-4994.
• Palladium-Catalyzed Formation and Stereoselective Isomerization of 5-Vinyloxazolines. Application to the Formal Synthesis of (S,S)-4-Amino-3-hydroxy-5-phenylpentanoic Acid Cook, Gregory R.; Shanker, P. Sathya Tetrahedron Lett. 1998, 39, 3405-3408.

Prior to NDSU

• An Asymmetric Synthesis of (-)-Epibatidine Trost, Barry M.; Cook, G.regory R. Tetrahedron Lett. 1996, 37, 7485-7488.
• Construction of Hydroxylated Alkaloids (±)-Mannonolactam, (±)-Deoxymannojirimycin, and (±)-Prosopinine through Aza-Annulation Cook, Gregory R.; Beholz, Lars G.; Stille, John R. J. Org. Chem. 1994, 59, 3575-3584.
• Aza-Annulation as a Route To Hydroxylated Alkaloid Lipids. The Synthesis of (±)-Prosopinine Cook, Gregory R.; Beholz, Lars G.; Stille, John R. Tetrahedron Lett. 1994, 35, 1669-1672.
• Stereochemical Consequences of the Lewis Acid-Promoted 3-Aza-Cope Rearrangement of N-Alkyl-N-allyl Examines Cook, Gregory R.; Stille, John R. Tetrahedron 1994, 50, 4105-4124.
• Studies of the Regiospecific 3-Aza-Cope Rearrangement Promoted by Electrophilic Reagents Barta, Nancy S.; Cook, Gregory R.; Landis, Margaret S.; Stille, John R. J. Org. Chem. 1992, 57, 7188-7194.
• Lewis Acid-Promoted 3-Aza-Cope Rearrangement of N-Alkyl-N-allylenamines Cook, Gregory R.; Barta, Nancy S.; Stille, John R. J. Org. Chem. 1992, 57, 461-467.
• Preparation and 3-Aza-Cope Rearrangement of N-Alkyl-N-allyl Examines Cook, Gregory R.; Stille, John R. J. Org. Chem. 1991, 56, 5578-5583.